CLINICAL REVIEW
Management of sickle cell disease in the community
Cite this as: BMJ 2014;348:g1765. 10TH APRIL 2014.
Summary points
All children with sickle cell disease should take penicillin twice a day until 5 years of age at least
Acute neurological symptoms in children and adults with sickle cell disease necessitate urgent referral to hospital
All patients should receive annual vaccination against influenza and other appropriate vaccinations where available
Patients living in most parts of Africa should use insecticide treated bed nets and take malarial prophylaxis
Children with severe types of sickle cell disease (HbSS and HbS/?0 thalassaemia) should be offered primary stroke prevention with annual transcranial Doppler scans and blood transfusion when resources allow this
Children and adults should be offered treatment with hydroxyurea if they have two or more episodes of severe acute pain in a year, or acute chest syndrome
Children, families, and adults should be offered education about sickle cell disease and managing its complications.
G Mohan.