Metabolic syndrome
Introduction

Metabolic syndrome is the medical term for a combination of diabetes, high blood pressure and obesity. It puts you at greater risk of heart disease, stroke and other conditions affecting blood vessels.
On their own, diabetes, high blood pressure and obesity can potentially damage your blood vessels, but having all three together is particularly dangerous.

What are the symptoms?
People with metabolic syndrome will have:
a waist circumference of 37 inches or more (in European men) or 31.5 inches or more (in European and South Asian women)
a waist circumference of 35.5 inches or more (in South Asian men)
high levels of triglycerides and low levels of HDL (“good” cholesterol) in the blood, which can lead to atherosclerosis – where arteries become clogged up by fatty substances such as cholesterol
high blood pressure that is consistently 140/90mmHg or higher
an inability to control blood sugar levels (insulin resistance)
an increased risk of developing blood clots, such as deep vein thrombosis (DVT)
a tendency to develop inflammation (irritation and swelling of body tissue)

What are the causes?
The factors that can cause metabolic syndrome are:
having an inherited genetic tendency towards insulin resistance
being overweight
being physically inactive
In other words, you can develop metabolic syndrome if you were born with a tendency to develop insulin resistance, and you go on to develop this by putting on weight and not exercising.
Metabolic syndrome is especially common in Asian and African-Carribean people, and in women with polycystic ovary syndrome (PCOS).

Dr G Mohan.