Dengue fever
BMJ 2015; 351 doi: http://dx.doi.org/10.1136/bmj.h4661 (Published 15 September 2015)
BMJ 2015;351:h4661

Update

Dengue fever is a globally important arboviral infection transmitted by the Aedes genus of mosquito (primarily A aegypti, but also A albopictus), found in tropical and subtropical regions
The infection is endemic in more than 100 countries, particularly the South East Asia region, western Pacific region, and the Americas

The incubation period is 3-14 days (average 7 days)

Clinical features include fever, headache, myalgia/arthralgia, and skin flushing/rash, together with leucopenia, thrombocytopenia, and increased liver function

Severe thrombocytopenia, haemorrhage, and plasma leakage are the key diagnostic features of the more severe forms of infection

Confirmatory tests include detection of viral antigen or nucleic acid and serology

Fluid therapy and the identification of the critical phase are the most important aspects of management

Dengue fever is a globally important arboviral infection transmitted by mosquitoes of the Aedes genus (primarily Aedes aegypti, but also A albopictus), an insect found in tropical and subtropical regions.1 Dengue infection causes a range of severe and non-severe clinical manifestations.

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G Mohan.