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      Anonymous
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      STORY OF THE WEEK
      Published in Respiratory Medicine
      Journal Scan / Research · March 29, 2023

      Effect of Training in Basic Life Support and Bystander-Performed CPR on Survival Outcomes of Out-of-Hospital Cardiac Arrest
      JAMA Network Open
      TAKE-HOME MESSAGE
      The authors of this retrospective cohort study aimed to evaluate the association between mandated population-level training in basic life support (BLS) and out-of-hospital cardiac arrest (OHCA) survival outcomes in Denmark. They found a significant association between 30-day survival in patients with OHCA and increased participation in BLS training. Bystander initiation of CPR accounted for 39% of this increase.

      The results of this study suggest that population-wide training in BLS has the potential to significantly increase survival in patients with OHCA.

      IMPORTANCE
      Strategies to improve survival from out-of-hospital cardiac arrest (OHCA) include mass education of laypersons with no official duty to respond to OHCA. In Denmark, basic life support (BLS) course attendance has been mandated by law in October 2006 for obtaining a driver’s license for all vehicles and in vocational education programs.

      OBJECTIVES
      To examine the association between yearly BLS course participation rate and bystander cardiopulmonary resuscitation (CPR) and 30-day survival from OHCA and to examine if bystander CPR rate acted as a mediator on the association between mass education of laypersons in BLS and survival from OHCA.

      DESIGN, SETTING, AND PARTICIPANTS
      This cohort study included outcomes for all OHCA incidents from the Danish Cardiac Arrest Register between 2005 and 2019. Data concerning BLS course participation were supplied by the major Danish BLS course providers.

      MAIN OUTCOMES AND MEASURES
      The main outcome was 30-day survival of patients who experienced OHCA. Logistic regression analysis was used to examine the association between BLS training rate, bystander CPR rate, and survival, and a bayesian mediation analysis was conducted to examine mediation.

      RESULTS
      A total of 51?057 OHCA incidents and 2?717?933 course certificates were included. The study showed that the annual 30-day survival from OHCA increased by 14% (odds ratio [OR], 1.14; 95% CI, 1.10-1.18; P?

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