GARDASIL
Human papillomavirus vaccines
How Supplied: Virus-like particles of the L1 protein of human papillomavirus (HPV): type 6 (20 microgram), type 11 (40 microgram), type 16 (40 microgram), type 18 (20 microgram).
Pre-filled syringe, 0.5ml.
Indications:
Prevention of premalignant cervical, vulvar and vaginal lesions, cervical cancer and external genital warts causally related to certain HPV types.
Adults:Schedule.
0.5ml by im inj at 0, 2 and 6 months.
Children:
Under 9 years, not recommended; 9—13 years, 0.5ml by im inj at 0 and 6 months or at 0, 2 and 6 months; 14 years and over, as adult.
General Warnings for Human papillomavirus vaccines
Contraindications:
Acute severe febrile illness. Pregnancy.
Precautions:
Thrombocytopenia, coagulation disorders. Impaired immune responsiveness.
Cervarix, Also, lactation.
Side Effects:
Pyrexia, inj site reactions, GI upset, headache.
Cervarix: Also, myalgia, arthralgia, skin disorders.
G Mohan.