Johns Hopkins Scientists Identify Third Critical Hormone in Type 2 Diabetes

Release Date: April 1, 2014

FAST FACTS:
It is well established that two hormones, glucagon and insulin, must work in perfect unison to maintain healthy blood sugar levels in the body.

Type 2 diabetes typically develops when glucagon, which stimulates sugar secretion, and insulin, which stimulates sugar absorption, are off balance.

Now, scientists at Johns Hopkins have discovered a third critical “player” in the development of type 2 diabetes–a hormone called kisspeptitn-1, which apparently carries out commands issued by glucagon and directly interferes with insulin production in the pancreas.- Team led by Dr Mehboob Hussain.

The discovery may prove to be a long-missing link in the understanding of the origins of the disease.

The researchers are currently designing therapies that block kisspeptin-1 from entering the insulin-producing cells of the pancreas.

How Exciting is this !!.

G Mohan.